Radical C-H bond functionalization provides a versatile approach for elaborating heterocycliccompounds.
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In addition, the protocol can be further applied in the synthesis of heterocycliccompounds like benzimidazoles.
3
The substrates are mostly heterocycliccompounds.
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As part of our continuing studies of polymer-supported pericyclic reactions for preparing biologically interesting heterocycliccompounds, we have introduced a traceless solid-phase synthesis of hexahydrocinnolines.
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Isovanillin has been shown to inhibit the metabolism of aromatic aldehydes by aldehyde oxidase, but its inhibition towards the heterocycliccompounds has not been studied.